Silicon Valley
Silicon Valley, as in the TV show and not the real region, is a show with several seasons about a small tech startup in Palo Alto called "Pied Piper". The nature of the company slightly changes over the show's run, but the basic idea is that their compression algorithm, which may or may not be possible in real life, is a threat to big bad evil megacorp Hooli (Google but fictional, which is weird because Google itself also apparently exists in-universe.
Why something as boring and an afterthought as a... compression algorithm? Turns out that's actually a pretty important piece of software, everything you download - on smartphones, game consoles and computers - is ridiculously huge without it, which makes download speeds unbearable. Still boring, but very practical. And Hooli wants it because despite what you've heard, a real life "data-geddon" is also very boring: It means corporations can't afford to offer cloud storage in return for data-mining, and that very much worries big tech companies like Hooli. It also means that the Pied Piper compression method is a potential moneymaker that Hooli's CEO tries to take via various means throughout the first few seasons.
Silicon Valley in Silicon Valley
Like real life, Silicon Valley isn't so much a place as a side of a place. When you picture the San Francisco Bay Area, you usually picture one of two things (if you've never been in person) like I do: The gay/lesbian culture (fair enough, moving on)... And Big Tech. Whether that's 1970s Microcomputers, IBM versus Compaq in the 80s, the rise of the World Wide Web in the 90s, the "tech gold rush" of the 00s, the social media giants of the 2010s, or the twilight of the USA as corruption usurps internet usage in the 2020s, there has always been an aspect of an "epic battle" to the business side of the region, a "David vs. Goliath" where Adam Smasher is usually fated to lose.
Unlike the Bible (even if it's to be considered real, it's still a recorded text with the intent of passing on extremely important - at least, relative to the ancient Hebrews - information) or Cyberpunk 2077 (which is simply saying "capitalism can become really, really bad, even Jesus said so", and CP2077 may not be relevant by the actual year 2077), the show itself is a comedy and doesn't so much have something to say as something to report: Like other shows of a similar nature, it draws heavily on little-known trivia of the real life tech industry. While it may not be as excitingly action-oriented as Glitch Techs, Silicon Valley is quick to point out some of the awful and underhanded things done by executives and even programmers in the history of consumer computing technology, and weave an amusing storyline from it that you'll probably laugh at if Glitch Techs x RP's themes are your jam.
Silicon Valley in Glitch Techs x RP
Silicon Valley is part of the Autopolis known as the San Andreas Metrobelt, a huge urban area stretching from San Francisco down to Tijuana that includes Los Angeles and Night City. The region of "Silicon Valley" is an idea rather than a specific place, but it roughly corresponds with San Francisco and it's surrounding area. The area is home to Hooli and it's parent company Abjad (including Nudle from Watch_dogs). Abjad is in turn just a larger example of the many companies that have set up shop in the Bay Area, lifted from other inspirations (such as Pal Labs from The Mitchells vs. The Machines), as well as Pied Piper itself.